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Direct observation of individual tubulin dimers binding to growing microtubules
The biochemical basis of microtubule growth has remained elusive for over 30 years despite being fundamental for both cell division and associated chemotherapy strategies. Here, we combine interferometric scattering microscopy with recombinant tubulin to monitor individual tubulins binding to and di...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462098/ https://ncbi.nlm.nih.gov/pubmed/30804205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815823116 |
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