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Insights into allosteric control of microtubule dynamics from a buried β‐tubulin mutation that causes faster growth and slower shrinkage

αβ‐tubulin subunits cycle through a series of different conformations in the polymer lattice during microtubule growing and shrinking. How these allosteric responses to different tubulin:tubulin contacts contribute to microtubule dynamics, and whether the contributions are evolutionarily conserved,...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Ye, Xuecheng, Kim, Tae, Geyer, Elisabeth A., Rice, Luke M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255507/
https://ncbi.nlm.nih.gov/pubmed/32077153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3842
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