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Direct observation of individual tubulin dimers binding to growing microtubules
The biochemical basis of microtubule growth has remained elusive for over 30 years despite being fundamental for both cell division and associated chemotherapy strategies. Here, we combine interferometric scattering microscopy with recombinant tubulin to monitor individual tubulins binding to and di...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462098/ https://ncbi.nlm.nih.gov/pubmed/30804205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815823116 |
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