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Dual actions of group B Streptococcus capsular sialic acid provide resistance to platelet-mediated antimicrobial killing

Circulating platelets have important functions in thrombosis and in modulating immune and inflammatory responses. However, the role of platelets in innate immunity to bacterial infection is largely unexplored. While human platelets rapidly kill Staphylococcus aureus, we found the neonatal pathogen g...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Uchiyama, Satoshi, Sun, Josh, Fukahori, Kyoko, Ando, Nao, Wu, Mengyou, Schwarz, Flavio, Siddiqui, Shoib S., Varki, Ajit, Marth, Jamey D., Nizet, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462088/
https://ncbi.nlm.nih.gov/pubmed/30910970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815572116
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