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Paired Siglec receptors generate opposite inflammatory responses to a human‐specific pathogen
Paired immune receptors display near‐identical extracellular ligand‐binding regions but have intracellular sequences with opposing signaling functions. While inhibitory receptors dampen cellular activation by recognizing self‐associated molecules, the functions of activating counterparts are less cl...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5350563/ https://ncbi.nlm.nih.gov/pubmed/28100677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695581 |
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