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Paired Siglec receptors generate opposite inflammatory responses to a human‐specific pathogen

Paired immune receptors display near‐identical extracellular ligand‐binding regions but have intracellular sequences with opposing signaling functions. While inhibitory receptors dampen cellular activation by recognizing self‐associated molecules, the functions of activating counterparts are less cl...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EMBO J
Päätekijät: Schwarz, Flavio, Landig, Corinna S, Siddiqui, Shoib, Secundino, Ismael, Olson, Joshua, Varki, Nissi, Nizet, Victor, Varki, Ajit
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350563/
https://ncbi.nlm.nih.gov/pubmed/28100677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695581
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