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Host and Pathogen Hyaluronan Signal Through Human Siglec-9 to Suppress Neutrophil Activation
Inhibitory CD33-related Siglec receptors regulate immune cell activation upon engaging ubiquitous sialic acids (Sias) on host cell surface glycans. Through molecular mimicry, Sia-expressing pathogen group B Streptococcus binds inhibitory human Siglec-9 (hSiglec-9) to blunt neutrophil activation and...
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| Gepubliceerd in: | J Mol Med (Berl) |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4766071/ https://ncbi.nlm.nih.gov/pubmed/26411873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-015-1341-8 |
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