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Decreased Erythrocyte Binding of Siglec-9 Increases Neutrophil Activation in Sickle Cell Disease
Oxidative stress and inflammation promotes vaso-occlusion in sickle cell disease (SCD). CD33-related Sialic acid-binding immunoglobulin-type lectins (CD33rSiglecs) are cell surface proteins that recognize sialic acids inhibit innate immune cell functions. We have shown that Siglec-9 on human neutrop...
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| Veröffentlicht in: | Blood Cells Mol Dis |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7002293/ https://ncbi.nlm.nih.gov/pubmed/31901888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2019.102399 |
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