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Paired Siglec receptors generate opposite inflammatory responses to a human‐specific pathogen

Paired immune receptors display near‐identical extracellular ligand‐binding regions but have intracellular sequences with opposing signaling functions. While inhibitory receptors dampen cellular activation by recognizing self‐associated molecules, the functions of activating counterparts are less cl...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Schwarz, Flavio, Landig, Corinna S, Siddiqui, Shoib, Secundino, Ismael, Olson, Joshua, Varki, Nissi, Nizet, Victor, Varki, Ajit
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350563/
https://ncbi.nlm.nih.gov/pubmed/28100677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695581
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