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O-Acetylation of Sialic Acid on Group B Streptococcus Inhibits Neutrophil Suppression and Virulence
Group B Streptococcus (GBS) requires capsular sialic acid (Sia) for virulence and partially modifies this sugar by O-acetylation. We describe serotype specific patterns of GBS Sia O-acetylation that can be manipulated by genetic and biochemical means. In vitro and in vivo assays demonstrate this sub...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640289/ https://ncbi.nlm.nih.gov/pubmed/20334627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100232 |
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