Molecular heterogeneity and early metastatic clone selection in testicular germ cell cancer development

BACKGROUND: Testicular germ cell cancer (TGCC), being the most frequent malignancy in young Caucasian males, is initiated from an embryonic germ cell. This study determines intratumour heterogeneity to unravel tumour progression from initiation until metastasis. METHODS: In total, 42 purified sample...

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發表在:Br J Cancer
Main Authors: Dorssers, Lambert C. J., Gillis, Ad J. M., Stoop, Hans, van Marion, Ronald, Nieboer, Marleen M., van Riet, Job, van de Werken, Harmen J. G., Oosterhuis, J. Wolter, de Ridder, Jeroen, Looijenga, Leendert H. J.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461884/
https://ncbi.nlm.nih.gov/pubmed/30739914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0381-1
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