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MEK1/2 inhibitor U0126, but not nimodipine, reduces upregulation of cerebrovascular contractile receptors after subarachnoid haemorrhage in rats

Vascular pathophysiological changes after haemorrhagic stroke, such as phenotypic modulation of the cerebral arteries and cerebral vasospasms, are associated with delayed cerebral ischemia (DCI) and poor outcome. The only currently approved drug treatment shown to reduce the risk of DCI and improve...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Christensen, Simon T., Johansson, Sara E., Radziwon-Balicka, Aneta, Warfvinge, Karin, Haanes, Kristian A., Edvinsson, Lars
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461292/
https://ncbi.nlm.nih.gov/pubmed/30978262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215398
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