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Human cerebrovascular contractile receptors are upregulated via a B-Raf/MEK/ERK-sensitive signaling pathway

BACKGROUND: Cerebral ischemia results in a rapid increase in contractile cerebrovascular receptors, such as the 5-hydroxytryptamine type 1B (5-HT(1B)), angiotensin II type 1 (AT(1)), and endothelin type B (ET(B)) receptors, in the vessel walls within the ischemic region, which further impairs local...

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Autori principali: Ahnstedt, Hilda, Säveland, Hans, Nilsson, Ola, Edvinsson, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023719/
https://ncbi.nlm.nih.gov/pubmed/21223556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-5
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