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Secondhand smoke exposure induces Raf/ERK/MAPK-mediated upregulation of cerebrovascular endothelin ET(A )receptors

BACKGROUND: Cigarette smoking enhances the risk of stroke. However, the underlying molecular mechanisms are largely unknown. The present study established an in vivo rat secondhand cigarette smoking (SHS) model and examined the hypothesis that SHS upregulates endothelin receptors with increased cere...

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Autors principals: Cao, Lei, Xu, Cang-Bao, Zhang, Yaping, Cao, Yong-Xiao, Edvinsson, Lars
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219602/
https://ncbi.nlm.nih.gov/pubmed/22044770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-109
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