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Inhibition of cerebrovascular raf activation attenuates cerebral blood flow and prevents upregulation of contractile receptors after subarachnoid hemorrhage

BACKGROUND: Late cerebral ischemia carries high morbidity and mortality after subarachnoid hemorrhage (SAH) due to reduced cerebral blood flow (CBF) and the subsequent cerebral ischemia which is associated with upregulation of contractile receptors in the vascular smooth muscle cells (SMC) via activ...

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Detalhes bibliográficos
Main Authors: Ansar, Saema, Maddahi, Aida, Edvinsson, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219635/
https://ncbi.nlm.nih.gov/pubmed/22032648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-107
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