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Chiral phosphoric acid-catalyzed enantioselective construction of structurally diverse benzothiazolopyrimidines

A highly efficient catalytic enantioselective [4+2] cycloaddition was developed between 2-benzothiazolimines and enecarbamates. A wide range of benzothiazolopyrimidines bearing three contiguous stereogenic centers was obtained in high to excellent yields and with excellent diastereo- and enantiosele...

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Détails bibliographiques
Publié dans:Chem Sci
Auteurs principaux: Jarrige, Lucie, Glavač, Danijel, Levitre, Guillaume, Retailleau, Pascal, Bernadat, Guillaume, Neuville, Luc, Masson, Géraldine
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461124/
https://ncbi.nlm.nih.gov/pubmed/31015920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc05581e
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