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An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere

The regio‐ and stereo‐specific oxygenation of polyunsaturated fatty acids is catalyzed by lipoxygenases (LOX); both Fe and Mn forms of the enzyme have been described. Structural elements of the Fe and Mn coordination spheres and the helical catalytic domain in which the metal center resides are high...

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Detalles Bibliográficos
Publicado en:Protein Sci
Main Authors: Pakhomova, Svetlana, Boeglin, William E., Neau, David B., Bartlett, Sue G., Brash, Alan R., Newcomer, Marcia E.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459989/
https://ncbi.nlm.nih.gov/pubmed/30861228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3602
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