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The 1.85 Å structure of an 8R-Lipoxygenase suggests a general model for lipoxygenase product specificity
Lipoxygenases (LOX) play pivotal roles in the biosynthesis of leukotrienes and other biologically active eicosanoids derived from arachidonic acid. A mechanistic understanding of substrate recognition, when lipoxygenases that recognize the same substrate generate different products, can be used to h...
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| Izdano u: | Biochemistry |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4715880/ https://ncbi.nlm.nih.gov/pubmed/19594169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900084m |
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