The structure of human 5-lipoxygenase

The synthesis of both pro-inflammatory leukotrienes and anti-inflammatory lipoxins requires the enzyme 5-lipoxygenase (5-LOX). 5-LOX activity is short-lived, apparently in part due to an intrinsic instability of the enzyme. We identified a 5-LOX-specific destabilizing sequence that is involved in or...

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Detaylı Bibliyografya
Asıl Yazarlar: Gilbert, Nathaniel C., Bartlett, Sue G., Waight, Maria T., Neau, David B., Boeglin, William E., Brash, Alan R., Newcomer, Marcia E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245680/
https://ncbi.nlm.nih.gov/pubmed/21233389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1197203
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