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The Structure of Human 15-Lipoxygenase-2 with a Substrate Mimic

Atherosclerosis is associated with chronic inflammation occurring over decades. The enzyme 15-lipoxygenase-2 (15-LOX-2) is highly expressed in large atherosclerotic plaques, and its activity has been linked to the progression of macrophages to the lipid-laden foam cells present in atherosclerotic pl...

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Detalhes bibliográficos
Main Authors: Kobe, Matthew J., Neau, David B., Mitchell, Caitlin E., Bartlett, Sue G., Newcomer, Marcia E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961679/
https://ncbi.nlm.nih.gov/pubmed/24497644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.543777
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