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Identification of the substrate access portal of 5-Lipoxygenase
The overproduction of inflammatory lipid mediators derived from arachidonic acid contributes to asthma and cardiovascular diseases, among other pathologies. Consequently, the enzyme that initiates the synthesis of pro-inflammatory leukotrienes, 5-lipoxygenase (5-LOX), is a target for drug design. Th...
Gorde:
| Argitaratua izan da: | Biochemistry |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4777300/ https://ncbi.nlm.nih.gov/pubmed/26427761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00930 |
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