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An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere

The regio‐ and stereo‐specific oxygenation of polyunsaturated fatty acids is catalyzed by lipoxygenases (LOX); both Fe and Mn forms of the enzyme have been described. Structural elements of the Fe and Mn coordination spheres and the helical catalytic domain in which the metal center resides are high...

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Dades bibliogràfiques
Publicat a:Protein Sci
Autors principals: Pakhomova, Svetlana, Boeglin, William E., Neau, David B., Bartlett, Sue G., Brash, Alan R., Newcomer, Marcia E.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459989/
https://ncbi.nlm.nih.gov/pubmed/30861228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3602
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