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Signal-induced PARP1-Erk synergism mediates IEG expression

A recently disclosed Erk-induced PARP1 activation mediates the expression of immediate early genes (IEG) in response to a variety of extra- and intra-cellular signals implicated in memory acquisition, development and proliferation. Here, we review this mechanism, which is initiated by stimulation-in...

詳細記述

保存先:
書誌詳細
出版年:Signal Transduct Target Ther
主要な著者: Cohen-Armon, Malka, Yeheskel, Adva, Pascal, John M.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459926/
https://ncbi.nlm.nih.gov/pubmed/30993015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-019-0042-0
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