LPS-Induced G-CSF Expression in Macrophages Is Mediated by ERK2, but Not ERK1

Granulocyte colony-stimulating factor (G-CSF) selectively stimulates proliferation and differentiation of neutrophil progenitors which play important roles in host defense against infectious agents. However, persistent G-CSF production often leads to neutrophilia and excessive inflammatory reactions...

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Bibliographic Details
Published in:PLoS One
Main Authors: Chang, Shwu-Fen, Lin, Shih-Shan, Yang, Hui-Ching, Chou, Yuan-Yi, Gao, Jhen-I, Lu, Shao-Chun
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483241/
https://ncbi.nlm.nih.gov/pubmed/26114754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129685
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