Malondialdehyde mediates oxidized LDL-induced coronary toxicity through the Akt-FGF2 pathway via DNA methylation

BACKGROUND: Oxidized LDL (oxLDL) is involved in the development of atherosclerotic heart disease through a mechanism that is not fully understood. In this study, we examined the role of malondialdehyde (MDA), an important oxidative stress epitope of oxLDL, in mediating coronary endothelial cytotoxic...

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Detalhes bibliográficos
Main Authors: Yang, Tzu-Ching, Chen, Yi-Jie, Chang, Shwu-Fen, Chen, Chu-Huang, Chang, Po-Yuan, Lu, Shao-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931320/
https://ncbi.nlm.nih.gov/pubmed/24490960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-21-11
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