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Neurons and astroglia govern microglial endotoxin tolerance through macrophage colony-stimulating factor receptor-mediated ERK1/2 signals

Endotoxin tolerance (ET) is a reduced responsiveness of innate immune cells like macrophages/monocytes to an endotoxin challenge following a previous encounter with the endotoxin. Although ET in peripheral systems has been well studied, little is known about ET in the brain. The present study showed...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Chu, Chun-Hsien, Wang, Shijun, Li, Chia-Ling, Chen, Shih-Heng, Hu, Chih-Fen, Chung, Yi-Lun, Chen, Shiou-Lan, Wang, Qingshan, Lu, Ru-Band, Gao, Hui-Ming, Hong, Jau-Shyong
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899166/
https://ncbi.nlm.nih.gov/pubmed/27132056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2016.04.015
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