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A PARP1-Erk2 synergism is required for stimulation-induced expression of immediate early genes

A PARP1-Erk2 synergism was required to generate synaptic long-term potentiation in the CA3-CA1 hippocampal connections. This molecular mechanism was associated with the recently identified pivotal role of polyADP-ribosylation in learning. High frequency electrical stimulation of cortical and hippoca...

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Publicat a:Gene Transl Bioinform
Autor principal: Cohen-Armon, M.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110042/
https://ncbi.nlm.nih.gov/pubmed/27857998
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