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A PARP1-Erk2 synergism is required for stimulation-induced expression of immediate early genes

A PARP1-Erk2 synergism was required to generate synaptic long-term potentiation in the CA3-CA1 hippocampal connections. This molecular mechanism was associated with the recently identified pivotal role of polyADP-ribosylation in learning. High frequency electrical stimulation of cortical and hippoca...

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Библиографические подробности
Опубликовано в: :Gene Transl Bioinform
Главный автор: Cohen-Armon, M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110042/
https://ncbi.nlm.nih.gov/pubmed/27857998
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