Pharmacophore-based design of novel 3-hydroxypyrimidine-2,4-dione subtypes as inhibitors of HIV reverse transcriptase-associated RNase H: tolerance of a nonflexible linker

Eitemau Tebyg

• 6-Biphenylmethyl-3-hydroxypyrimidine-2,4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H
  gan: Wang, Lei, et al.
  Cyhoeddwyd: (2018)
• 6-Arylthio-3-hydroxypyrimidine-2,4-diones potently inhibited HIV reverse transcriptase-associated RNase H with antiviral activity
  gan: Wang, Lei, et al.
  Cyhoeddwyd: (2018)
• Design, Synthesis and Biological Evaluations of N-Hydroxy thienopyrimidine-2,4-diones as Inhibitors of HIV Reverse Transcriptase-Associated RNase H
  gan: Kankanala, Jayakanth, et al.
  Cyhoeddwyd: (2017)
• Double-winged 3-Hydroxypyrimidine-2,4-diones: Potent and Selective Inhibition against HIV-1 RNase H with Significant Antiviral Activity
  gan: Vernekar, Sanjeev Kumar V., et al.
  Cyhoeddwyd: (2017)
• 3-Hydroxypyrimidine-2,4-dione-5-N-benzylcarboxamides potently inhibit HIV-1 integrase and RNase H
  gan: Wu, Bulan, et al.
  Cyhoeddwyd: (2016)