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Regulation of Krüppel-like factor 8 by the NEDD4 E3 ubiquitin ligase

Krüppel-like factor 8 (KLF8) plays many important roles in various diseases, especially cancer. Previous studies have shown that KLF8 is regulated by ubiquitylation. The molecular mechanism underlying this posttranslational modification of KLF8, however, has not been investigated. Reported here is o...

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Vydáno v:Am J Transl Res
Hlavní autoři: Sun, Aiqin, Hao, Jie, Yu, Lin, Lahiri, Satadru K, Yang, Wannian, Lin, Qiong, Zhao, Jihe
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456509/
https://ncbi.nlm.nih.gov/pubmed/30972179
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