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ERK2 phosphorylates Krüppel-like factor 8 protein at serine 48 to maintain its stability

Krüppel-like factor 8 (KLF8) plays important roles in cancer and is strictly regulated by various post-translational modifications such as sumoylation, acetylation, ubiquitylation and PARylation. Here we report a novel phosphorylation of KLF8 by ERK2 responsible and critical for the stability of KLF...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Lahiri, Satadru K, Lu, Heng, Mukherjee, Debarati, Yu, Lin, Zhao, Jihe
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889709/
https://ncbi.nlm.nih.gov/pubmed/27293988
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