Identification of epidermal growth factor receptor and its inhibitory microRNA141 as novel targets of Krüppel-like factor 8 in breast cancer

Krüppel-like factor 8 (KLF8) is a dual transcriptional factor critical for breast cancer progression. Epidermal growth factor receptor (EGFR) is frequently overexpressed in aggressive such as triple-negative breast cancer and associated with poor clinical outcomes. Here we report a novel KLF8-EGFR s...

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Опубликовано в: :Oncotarget
Главные авторы: Li, Tianshu, Lu, Heng, Mukherjee, Debarati, Lahiri, Satadru K., Shen, Chao, Yu, Lin, Zhao, Jihe
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2015
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673276/
https://ncbi.nlm.nih.gov/pubmed/26025929
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