Krüppel-like factor 8 activates the transcription of C-X-C cytokine receptor type 4 to promote breast cancer cell invasion, transendothelial migration and metastasis

Krüppel-like factor 8 (KLF8) has been strongly implicated in breast cancer metastasis. However, the underlying mechanisms remain largely unknown. Here we report a novel signaling from KLF8 to C-X-C cytokine receptor type 4 (CXCR4) in breast cancer. Overexpression of KLF8 in MCF-10A cells induced CXC...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Mukherjee, Debarati, Lu, Heng, Yu, Lin, He, Chunjiang, Lahiri, Satadru K., Li, Tianshu, Zhao, Jihe
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029647/
https://ncbi.nlm.nih.gov/pubmed/26993780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8083
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