The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells

BACKGROUND: EGFR-dependent cell migration plays an important role in lung cancer progression. Our previous study observed that the HECT E3 ubiquitin ligase NEDD4 is significantly correlated with tumor metastasis and required for migration and invasion signaling of EGFR in gastric cancer cells. Howev...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Shao, Genbao, Wang, Ranran, Sun, Aiqin, Wei, Jing, Peng, Ke, Dai, Qian, Yang, Wannian, Lin, Qiong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817799/
https://ncbi.nlm.nih.gov/pubmed/29455656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0784-2
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