The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells

BACKGROUND: EGFR-dependent cell migration plays an important role in lung cancer progression. Our previous study observed that the HECT E3 ubiquitin ligase NEDD4 is significantly correlated with tumor metastasis and required for migration and invasion signaling of EGFR in gastric cancer cells. Howev...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cancer
Main Authors: Shao, Genbao, Wang, Ranran, Sun, Aiqin, Wei, Jing, Peng, Ke, Dai, Qian, Yang, Wannian, Lin, Qiong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817799/
https://ncbi.nlm.nih.gov/pubmed/29455656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0784-2
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