The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells

BACKGROUND: EGFR-dependent cell migration plays an important role in lung cancer progression. Our previous study observed that the HECT E3 ubiquitin ligase NEDD4 is significantly correlated with tumor metastasis and required for migration and invasion signaling of EGFR in gastric cancer cells. Howev...

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Dettagli Bibliografici
Pubblicato in:Mol Cancer
Autori principali: Shao, Genbao, Wang, Ranran, Sun, Aiqin, Wei, Jing, Peng, Ke, Dai, Qian, Yang, Wannian, Lin, Qiong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817799/
https://ncbi.nlm.nih.gov/pubmed/29455656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0784-2
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