Učitavanje...

Deleting full length titin versus the titin M-band region leads to differential mechanosignaling and cardiac phenotypes.

BACKGROUND: Titin is a giant elastic protein that spans the half-sarcomere from Z-disk to M-band. It acts as a molecular spring and mechanosensor and has been linked to striated muscle disease. The pathways that govern titin dependent cardiac growth and contribute to disease are diverse and difficul...

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Bibliografski detalji
Izdano u:Circulation
Glavni autori: Radke, Michael H., Polack, Christopher, Methawasin, Mei, Fink, Claudia, Granzier, Henk L., Gotthardt, Michael
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453709/
https://ncbi.nlm.nih.gov/pubmed/30700140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.118.037588
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