Single cell analysis of clonal architecture in acute myeloid leukaemia

We used single cell Q-PCR on a micro-fluidic platform (Fluidigm) to analyse clonal, genetic architecture and phylogeny in acute myeloid leukaemia (AML) using selected mutations. Ten cases of NPM1c mutant AML were screened for 111 mutations that are recurrent in AML and cancer. Clonal architectures w...

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Bibliografiska uppgifter
I publikationen:Leukemia
Huvudupphovsmän: Potter, Nicola, Miraki-Moud, Farideh, Ermini, Luca, Titley, Ian, Vijayaraghavan, Gowri, Papaemmanuil, Elli, Campbell, Peter, Gribben, John, Taussig, David, Greaves, Mel
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451634/
https://ncbi.nlm.nih.gov/pubmed/30568172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0319-2
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