Wird geladen...

Mesenchymal niche remodeling impairs hematopoiesis via stanniocalcin 1 in acute myeloid leukemia

Acute myeloid leukemia (AML) disrupts the generation of normal blood cells, predisposing patients to hemorrhage, anemia, and infections. Differentiation and proliferation of residual normal hematopoietic stem and progenitor cells (HSPCs) are impeded in AML-infiltrated bone marrow (BM). The underlyin...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Waclawiczek, Alexander, Hamilton, Ashley, Rouault-Pierre, Kevin, Abarrategi, Ander, Albornoz, Manuel Garcia, Miraki-Moud, Farideh, Bah, Nourdine, Gribben, John, Fitzgibbon, Jude, Taussig, David, Bonnet, Dominique
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260026/
https://ncbi.nlm.nih.gov/pubmed/32364536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133187
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!