Single cell analysis of clonal architecture in acute myeloid leukaemia

We used single cell Q-PCR on a micro-fluidic platform (Fluidigm) to analyse clonal, genetic architecture and phylogeny in acute myeloid leukaemia (AML) using selected mutations. Ten cases of NPM1c mutant AML were screened for 111 mutations that are recurrent in AML and cancer. Clonal architectures w...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Potter, Nicola, Miraki-Moud, Farideh, Ermini, Luca, Titley, Ian, Vijayaraghavan, Gowri, Papaemmanuil, Elli, Campbell, Peter, Gribben, John, Taussig, David, Greaves, Mel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451634/
https://ncbi.nlm.nih.gov/pubmed/30568172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0319-2
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