Single-cell mutational profiling and clonal phylogeny in cancer

The development of cancer is a dynamic evolutionary process in which intraclonal, genetic diversity provides a substrate for clonal selection and a source of therapeutic escape. The complexity and topography of intraclonal genetic architectures have major implications for biopsy-based prognosis and...

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Detalhes bibliográficos
Main Authors: Potter, Nicola E., Ermini, Luca, Papaemmanuil, Elli, Cazzaniga, Giovanni, Vijayaraghavan, Gowri, Titley, Ian, Ford, Anthony, Campbell, Peter, Kearney, Lyndal, Greaves, Mel
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847780/
https://ncbi.nlm.nih.gov/pubmed/24056532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.159913.113
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