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Single-cell mutational profiling and clonal phylogeny in cancer
The development of cancer is a dynamic evolutionary process in which intraclonal, genetic diversity provides a substrate for clonal selection and a source of therapeutic escape. The complexity and topography of intraclonal genetic architectures have major implications for biopsy-based prognosis and...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3847780/ https://ncbi.nlm.nih.gov/pubmed/24056532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.159913.113 |
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