Single cell analysis of clonal architecture in acute myeloid leukaemia

We used single cell Q-PCR on a micro-fluidic platform (Fluidigm) to analyse clonal, genetic architecture and phylogeny in acute myeloid leukaemia (AML) using selected mutations. Ten cases of NPM1c mutant AML were screened for 111 mutations that are recurrent in AML and cancer. Clonal architectures w...

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Detaylı Bibliyografya
Yayımlandı:Leukemia
Asıl Yazarlar: Potter, Nicola, Miraki-Moud, Farideh, Ermini, Luca, Titley, Ian, Vijayaraghavan, Gowri, Papaemmanuil, Elli, Campbell, Peter, Gribben, John, Taussig, David, Greaves, Mel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451634/
https://ncbi.nlm.nih.gov/pubmed/30568172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0319-2
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