Versatile humanized niche model enables study of normal and malignant human hematopoiesis

The BM niche comprises a tightly controlled microenvironment formed by specific tissue and cells that regulates the behavior of hematopoietic stem cells (HSCs). Here, we have provided a 3D model that is tunable in different BM niche components and useful, both in vitro and in vivo, for studying the...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Abarrategi, Ander, Foster, Katie, Hamilton, Ashley, Mian, Syed A., Passaro, Diana, Gribben, John, Mufti, Ghulam, Bonnet, Dominique
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2017
Fag:
Brief Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5272182/
https://ncbi.nlm.nih.gov/pubmed/28067666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI89364
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