Ectopic Humanized Mesenchymal Niche in Mice Enables Robust Engraftment of Myelodysplastic Stem Cells

Myelodysplastic syndromes (MDS) are clonal stem cell diseases characterized mainly by ineffective hematopoiesis. Here, we present an approach that enables robust long-term engraftment of primary MDS stem cells (MDS-SC) in mice by implantation of human mesenchymal cell–seeded scaffolds. Critically fo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Blood Cancer Discov
Päätekijät: Mian, Syed A., Abarrategi, Ander, Kong, Kar Lok, Rouault-Pierre, Kevin, Wood, Henry, Oedekoven, Caroline A., Smith, Alexander E., Batsivari, Antoniana, Ariza-McNaughton, Linda, Johnson, Peter, Snoeks, Thomas, Mufti, Ghulam J., Bonnet, Dominique
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Association for Cancer Research 2020
Aiheet:
Research Brief
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610449/
https://ncbi.nlm.nih.gov/pubmed/33778768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2643-3230.BCD-20-0161
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