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Diversification of the TCR β Locus V(β) Repertoire by CTCF
The architectural protein CTCF regulates the conformation and recombination of antigen receptor loci. To study the importance of CTCF in Tcrb locus repertoire formation, we created a conditional knockout mouse line that deletes Ctcf early during thymocyte development. We observed an incomplete block...
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| Publicado no: | Immunohorizons |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6450071/ https://ncbi.nlm.nih.gov/pubmed/30957077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.1800072 |
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