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Assembled DJβ Complexes can Influence TCRβ Chain Selection and Peripheral Vβ Repertoire

TCRβ chain repertoire of peripheral αβ T cells is generated through the step-wise assembly and subsequent selection of TCRβ variable region exons during thymocyte development. To evaluate the influence of a two-step recombination process on Vβ rearrangement and selection, we generated mice with a pr...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Carpenter, Andrea C., Yang-Iott, Katherine S., Chao, Linda H., Nuskey, Beth, Whitlow, Scott, Alt, Frederick W., Bassing, Craig H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703067/
https://ncbi.nlm.nih.gov/pubmed/19380806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803270
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