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TCRβ Feedback Signals Inhibit the Coupling of Recombinationally Accessible Vβ14 Segments with DJβ Complexes

Antigen receptor allelic exclusion is thought to occur through mono-allelic initiation and subsequent feedback inhibition of recombinational accessibility. However, our previous analysis of mice containing a V(D)J recombination reporter inserted into Vβ14 (Vβ14(Rep)) indicated that Vβ14 chromatin ac...

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Detalhes bibliográficos
Main Authors: Yang-Iott, Katherine S., Carpenter, Andrea C., Rowh, Marta A. W., Steinel, Natalie, Brady, Brenna L., Hochedlinger, Konrad, Jaenisch, Rudolf, Bassing, Craig H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873682/
https://ncbi.nlm.nih.gov/pubmed/20042591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900723
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