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Position Dependent Silencing of Germline Vβ Segments on TCRβ Alleles Containing Pre-Assembled VβDJβCβ1 Genes
The genomic organization of TCRβ loci enables Vβ-to-DJβ2 rearrangements on alleles with assembled VβDJβCβ1 genes, which could have deleterious physiologic consequences. To determine whether such Vβ rearrangements occur and if so how they might be regulated, we analyzed mice with TCRβ alleles contain...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933292/ https://ncbi.nlm.nih.gov/pubmed/20709953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903098 |
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