An ectopic CTCF-dependent transcriptional insulator influences the choice of Vβ gene segments for VDJ recombination at TCRβ locus

Insulators regulate transcription as they modulate the interactions between enhancers and promoters by organizing the chromatin into distinct domains. To gain better understanding of the nature of chromatin domains defined by insulators, we analyzed the ability of an insulator to interfere in VDJ re...

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Detaylı Bibliyografya
Asıl Yazarlar: Shrimali, Sweety, Srivastava, Surabhi, Varma, Garima, Grinberg, Alex, Pfeifer, Karl, Srivastava, Madhulika
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
Konular:
Gene Regulation, Chromatin and Epigenetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439925/
https://ncbi.nlm.nih.gov/pubmed/22718969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks556
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