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Chromatin Domain Organization of the TCRb Locus and Its Perturbation by Ectopic CTCF Binding

CTCF-mediated chromatin interactions influence organization and function of mammalian genome in diverse ways. We analyzed the interactions among CTCF binding sites (CBS) at the murine TCRb locus to discern the role of CTCF-mediated interactions in the regulation of transcription and VDJ recombinatio...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Rawat, Pratishtha, Jalan, Manisha, Sadhu, Ananya, Kanaujia, Abhilasha, Srivastava, Madhulika
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394274/
https://ncbi.nlm.nih.gov/pubmed/28137913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00557-16
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