An ectopic CTCF-dependent transcriptional insulator influences the choice of Vβ gene segments for VDJ recombination at TCRβ locus

Insulators regulate transcription as they modulate the interactions between enhancers and promoters by organizing the chromatin into distinct domains. To gain better understanding of the nature of chromatin domains defined by insulators, we analyzed the ability of an insulator to interfere in VDJ re...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shrimali, Sweety, Srivastava, Surabhi, Varma, Garima, Grinberg, Alex, Pfeifer, Karl, Srivastava, Madhulika
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439925/
https://ncbi.nlm.nih.gov/pubmed/22718969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks556
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados